![]() ![]() Original Assignee Novartis Finance Corp Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.) Vernooij Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.) Expired - Fee Related Application number US08/454,876 Inventor Thomas D. Google Patents Chemically regulatable and anti-pathogenic DNA sequences and uses thereofĭownload PDF Info Publication number US5804693A US5804693A US08/454,876 US45487695A US5804693A US 5804693 A US5804693 A US 5804693A US 45487695 A US45487695 A US 45487695A US 5804693 A US5804693 A US 5804693A Authority US United States Prior art keywords plant gene sequence dna plasmid Prior art date Legal status (The legal status is an assumption and is not a legal conclusion. Google Patents US5804693A - Chemically regulatable and anti-pathogenic DNA sequences and uses thereof USA 80, 726–730.US5804693A - Chemically regulatable and anti-pathogenic DNA sequences and uses thereof (1983) Rapid similarity searches of nucleic acid and protein databanks. (1990) Rapid and sensitive sequence comparison with FASTP and FASTA. (1985) Rapid and sensitive protein similarity searches. (1982) A high speed, high capacity homology matrix zooming through SV40 and polyoma. ![]() (1994) Issues in searching molecular sequence databases. (1994) CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, positions-specific gap penalties and weight matrix choice. (1978) Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins. ![]() (1974) Conformational parameters for amino acids in helical, beta-sheet, and random coil regions calculated from proteins. (1989) A computer program for choosing optimal oligonucleotides for filter hybridization, sequencing and in vitro amplification of DNA. (1984) The codon preference plot graphic analysis of protein coding sequences and prediction of gene expression. Gribskov, M., Devereux, J., and Burgess, R. (1982) Recognition of protein coding regions in DNA sequences. Oxford Molecular, Oxford, England.įickett, J. Oxford Molecular Group (1998) MacVector 6.5 User Guide. This process is experimental and the keywords may be updated as the learning algorithm improves. These keywords were added by machine and not by the authors. MacVector also comes with a module for contig assembly, called AssemblyLIGN. At the time of writing, the version of MacVector available was 6.5. It provides all of the most commonly used nucleic acid and protein analysis tools and also provides access via the Internet to the public Entrez databases at the National Center for Biotechnology Information (NCBI). It is an integrated comprehensive sequence analysis program that runs on the Macintosh. MacVector™, from Oxford Molecular Group, Campbell CA, is one such computer package. It is evident by now that efficiently performing the above operations on thousands or millions of base pairs by hand is so difficult as to be impossible, and computer programs that do sequence analysis are becoming more and more ubiquitous in laboratories practicing molecular biology. Whether a researcher is working on a genome project, or is cloning and characterizing a gene of interest, the ability to manipulate, analyze, and annotate sequence data is becoming increasingly important.
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